A novel one-pot synthesis of 2-arylpyrazoloquinolinone derivatives

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题名:	A novel one-pot synthesis of 2-arylpyrazoloquinolinone derivatives
作者:	En-Chiuan Chang;Ya-Lan Wen;Chun-Hsi Chang;Yun-Hwei Shen;Shaw-Bing Wen;Mou-Yung Yeh;Fung Fuh Wong
关键词:	2-Arylpyrazolo[3,4-c]quinolin-4(5H)-ones;2-Arylpyrazolo[4,3-c]quinolin-4(5H)-ones;3-Aryl sydnone;1,3-Dipolar cycloaddition;Suzuki coupling reaction;Adenosine receptor
日期:	2012-07
上传时间:	2012-09-24T06:41:58Z (UTC)
摘要:	Two regioisomers of 2-arylpyrazolo[3,4-c]quinolin-4(5H)-ones and 2-arylpyrazolo[4,3-c]quinolin-4(5H)-ones were synthesized by utilizing 3-arylsydnones, ethyl 3-bromopropynoate, and 2-aminophenylboronic acid pinacol ester in presence of catalytic agent Pd(PPh3)4. This efficient one-pot synthesis methodology involved 1,3-dipolar cycloaddition, Suzuki coupling reaction, and intramolecular cyclization three sequence steps.
關聯:	Tetrahedron Volume 68, Issue 29, 22 July 2012, Pages 5920–5924
显示于类别:	[護理系] 期刊論文

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