Meiho University Institutional Repository:Item 987654321/2194
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    Please use this identifier to cite or link to this item: http://ir.meiho.edu.tw/ir/handle/987654321/2194


    Title: Oxygenated Cembranoids from the Soft Coral Sinularia flexibilis
    Authors: Ching-Chyuan Su;Bing-Sang Wong;Chuen Chin;Yu-Jen Wu;Jui-Hsin Su
    Contributors: 健康暨護理學院
    Date: 2013
    Issue Date: 2013-10-11T07:50:08Z (UTC)
    Abstract: Chemical examination of the Taiwanese soft coral Sinularia flexibilis led to the
    isolation of five cembrane-based diterpenoids 1–5, including two new metabolites,
    11-acetylsinuflexolide (1) and 11-acetyldihydrosinuflexolide (2). The structures of the new
    metabolites were determined based on extensive spectroscopic analysis, particularly mass
    spectrometry and 2D NMR (1H–1H COSY, HMQC, HMBC, and NOESY) spectroscopy.
    Metabolites 1, 3 and 4 exhibited moderate to weak cytotoxicity to human tumor cell lines,
    HeLa, HEp-2, MCF-7 and MDA-MB-231.
    Relation: Molecular Sciences
    Appears in Collections:[Department of Beauty Science] Papers

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