Meiho University Institutional Repository:Item 987654321/2574
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    题名: Proteomic analysis of the differences in orbital protein expression in thyroid orbitopathy
    作者: Kai-Chun Cheng
    Han-Hsiang Huang
    Chun-Tzu Hung
    Cheng-Chi Chen
    Wen-Chuan Wu
    Jau-Ling Suen
    Kuo-Jen Chen
    Yu-Jen Wu
    Cheng-Hsien Chang
    贡献者: 健康暨護理學院
    日期: 2013
    上传时间: 2014-10-17T03:29:27Z (UTC)
    摘要: Background Thyroid orbitopathy (TO) is a multi-system inflammatory
    disease characterized by orbital congestion, ocular
    surface disorders, restrictive myopathy, and skin lesions.
    The molecular and cellular processes of pathogenic formation
    of TO orbital fat tissues are not fully understood. In this study,
    a comparative proteomic analysis was conducted to investigate
    the importance of some differential proteins of orbital fat
    tissues in TO.
    Methods The differential proteins were analyzed by comparing
    the two-dimensional gel electrophoresis (2-DE) maps of
    the orbital fat tissues of TO with those of normal orbital fat
    tissues. The 2-DE results were further verified byWestern blot
    and immunohistochemistry.
    關聯: Graefes Arch Clin Exp Ophthalmol
    显示于类别:[美容系] 期刊論文

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