Meiho University Institutional Repository:Item 987654321/2762
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    Please use this identifier to cite or link to this item: http://ir.meiho.edu.tw/ir/handle/987654321/2762


    Title: 利用低劑量aspirin治療高血脂症誘發動脈活性下降、血球黏著及內皮損傷之研究子計畫(二) 計畫名稱:低劑量aspirin治療高血脂症誘發血球黏著之研究
    Authors: 沈國屏;林慧麗
    Keywords: aspirin;hyperlipidemia;adhesion molecules
    Date: 2015-06-11
    Issue Date: 2015-06-11T08:00:46Z (UTC)
    Abstract: 將SD大鼠分成3組,空白組餵食正常飼料,實驗組餵食高脂肪飼料,預防組餵食高脂肪飼料及每日口服5 mg/kg aspirin,時間各為8週。單獨餵食高脂肪飼料的大鼠,可以發現其體重、膽固醇、三酸甘油脂及胰島素明顯比餵食正常飼料組的大鼠高。血管的收縮受到高脂飼料的影響明顯增加。餵食高脂肪飼料會誘發大鼠過氧化物質malondialdehyde (MDA)增加。血小板的黏著受到高脂飼料的影響明顯增加。預防組大鼠的體重、膽固醇、三酸甘油脂及胰島素明顯比餵食高脂肪飼料組的大鼠低;血管的收縮受到aspirin的影響明顯減少;過氧化物質malondialdehyde (MDA)也減少。Aspirin能抑制高血脂症誘發之血小板黏著的反應。
    Appears in Collections:[Department of Nursing] Research Projects

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