This study evaluated the effectiveness of a health care intervention program on the health indicators of patients with early-stage chronic kidney disease (CKD).The study participants consisted of outpatients from a regional hospital in Southern Taiwan, and cases included CKD patients and those suffering from Stage 1, Stage 2, and Stage 3a of the disease, with cases from the nephrology department forming the experimental group, and cases from other departments forming the control group.After 3 times individualized health education interventions for patients with early-stage CKD can significantly improve patients’ health-related indicators.