Meiho University Institutional Repository:Item 987654321/2789
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    Please use this identifier to cite or link to this item: http://ir.meiho.edu.tw/ir/handle/987654321/2789


    Title: Evaluating the Effects of the Components of Metabolic Syndrome, Fatty LiverandLiverFunctiononChronic Hepatitis C: Data Analysis of Adult Health Examinations
    Authors: Chen, Chien-Hua;Chen, Mei-Chia;Hsiao, Szu-Mei;Lin, Pi-Li;Sun, Chien-An;Chou, Yu-Ching;Yang, Tsan
    Keywords: metabolic syndrome;chronic hepatitis C;liver function;health examination
    Date: 2015-08-19
    Issue Date: 2015-08-24T03:00:11Z (UTC)
    Abstract: Objective: The purpose of this study was to investigate the influential factors of chronichepatitis C.
    Methods: This was a cross-sectional study.Subjects aged 40 through 70, who received physical check-up from January 1, 2007 to December 31, 2011 in a hospital in central Taiwan, were included in this study. Among them, 200 cases had a diagnosis of chronic hepatitis C and 744 of them were free of hepatitis C. Physical data was obtained from health examinations and blood tests. Data were analyzed using SPSS for Windows, version 18.0. Results: The prevalence rate of metabolic syndrome (MetS)in participants with chronic hepatitis C was 23.3%. The prevalence of chronic hepatitis C in women and participants aged 40–55yearswas high (35.6% for women and 15.7% for men; 33.8% for participants aged 40–55yearsand 16.9% for participants aged 56–70years). Regarding composite factors for MetS, the prevalence of chronic hepatitis Cin participants with a raised fasting plasma glucose (FPG) or hypertensionwas higher than that of participants without chronic hepatitis C (35.2% vs. 16.6%and25.7% vs. 17.3%for hyperglycemiaandhypertension, respectively); the results were all statistically significant. Logistic regression analysis was preformed to predict the influential factors of chronichepatitis C. The results indicated that women and participants aged 40–55yearsexhibited a relatively higherrisk ofchronichepatitis C. In addition, participants with MetS, hyperglycemia, hypertension, or abnormal liver function exhibited a comparatively higherrisk of chronichepatitis C; the odds ratios for these participants were 1.72 (95% confidence interval [CI]= 1.10–2.70), 1.76 (95%CI = 1.08–2.89), 2.33 (95%CI = 1.61–3.37), and 2.40 (95%CI = 1.62–3.55), respectively.
    Conclusion: This study indicatedthat abnormal liver function, MetSand its composite factors were correlated with chronichepatitis C. Copyright © WJMMS, all rights reserved.
    Appears in Collections:[Department of Health Business Administration] Papers

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