The increasing prevalence of metabolic syndrome (MetS) has become an important issue worldwide. Metabolic comorbidities ofhypertension, obesity, and hyperlipidemia are shown as important risk factors for incident gout.The purpose of this study was toinvestigate the relationship between hyperuricemia and MetS. This is a cross-sectional study.The effective sample included 21,544individuals who received worker health examinations at a local teaching hospital in Changhua County from 2008â¼2012. We used
multiple logistic regression analysis to investigate the influences of hyperuricemia on MetS. The results showed that individualswith MetS had significantly higher blood pressure, fasting plasma glucose, triglycerides, waist circumference, and high-densitylipoprotein cholesterol than those without MetS (ð < 0.001). Multiple logistic regression analysis revealed hyperuricemia to be animportant factor of MetS. The risk of developing MetS is higher with high levels of serum uric acid (SUA) and the odds ratio (OR)
of having MetS is 4.98 times higher for Tertile 3 than for Tertile 1 (95% CI = 4.16â5.97) and 4 times higher for Quartile 4 than forQuartile 1 (95% CI = 3.59â4.46). In conclusion, males are more likely to develop MetS than females, and the risk of having MetSincreases with age and SUA concentration.
