Meiho University Institutional Repository:Item 987654321/3339
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    题名: Risk of infection following colonoscopy and sigmoidoscopy in symptomatic patients
    作者: Lin, Jiun-Nong;Wang, Chang-Bi;Yang, Chih-Hui;Lai, hung-Hsu;Lin, Hsi-Hsun
    日期: 2017-06-11
    上传时间: 2017-07-21T04:52:52Z (UTC)
    摘要: Background and study aims Previous studies describingthe incidence of infection after colonoscopy and sigmoidoscopyare limited. The aim of this study was to determinethe incidence of infection, and to propose a nomogram topredict the probability of infection following colonoscopyand sigmoidoscopy in symptomatic patients.
    Patients and methods A nationwide retrospective studywas conducted by analyzing the National Health Insurance
    Research Database of Taiwan. The incidence of infectionwithin 30 days after colonoscopy and sigmoidoscopy was
    assessed and compared with a control group matched at aratio of 1:1 based on age, sex, and the date of examination.
    Results In all, 112 543 patients who underwent colonoscopyor sigmoidoscopy and 112 543 matched patients who
    did not undergo these procedures were included. The overallincidence of infection within 30 days after colonoscopy
    and sigmoidoscopy was 0.37%, which was significantlyhigher than that of the control group (0.04%; P < 0.001). Diverticulitis,peritonitis, and appendicitis were the mostcommon infections. Patients who underwent colonoscopy
    or sigmoidoscopy had a 9.38-fold risk of infection (95%confidence interval, 6.81 – 12.93; P < 0.001) compared with
    the control group. The predicted infection-free rates of thenomogram were closely aligned with the actual infectionfree
    rates, with a bootstrapping concordance index of0.763.Conclusions Colonoscopy and sigmoidoscopy are associated
    with an increased risk of infection, which may occurafter these procedures. Our nomogram may provide clinicianswith an easy tool to evaluate the risk of infection aftercolonoscopy and sigmoidoscopy in symptomatic patients.
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