Meiho University Institutional Repository:Item 987654321/3376
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    Please use this identifier to cite or link to this item: http://ir.meiho.edu.tw/ir/handle/987654321/3376


    Title: 奇異果萃取物美白活性之檢測與評估
    Authors: 王正隆;鄭智交
    Keywords: 奇異果;黑色素;酪胺酸酶
    Date: 2017-10-25
    Issue Date: 2017-10-26
    Abstract: 本計畫之目的乃藉由細胞外與細胞內美白活性評估系統進行市售奇異果萃取物其美白功效之檢測與評估。
    人類的膚色主要由表皮層的黑色素、真皮層的胡蘿蔔素及血液中的血紅素所決定。其中又以表皮層的黑色素含量影響最大。而黑色素主要由黑色素細胞所合成,其合成過程受到嚴密的調控。綜觀整個黑色素生合成過程,酪胺酸酶扮演一關鍵性角色,不但參與三個步驟的催化反應,更是生合成第一步驟的關鍵酵素。因此,利用細胞外酪胺酸酶活性評估系統,便可快速評估奇異果萃取物抑制酪胺酸酶活性之程度及其皮膚美白之潛力。
    實驗結果顯示:市售的奇異果萃取物能有效抑制酪胺酸酶活性,當奇異果萃取液濃度達15%時,抑制酪胺酸酶的活性可達40%,而檢測其對細胞毒性的影響,並不明顯(data not show)。因此,奇異果萃取液調製為美白化粧品的成份具有市場的潛力。
    Appears in Collections:[Department of Nursing] Research Projects

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