Our continuous chemical study of a cultured octocoral Briareum stechei led to the isolation
of four new briarane diterpenoids, briarenols Q–T (1–4). The structures of new metabolites 1–4 were
established by spectroscopic methods, and compounds 3 and 4 were found to inhibit the generation
of inducible nitric oxide synthase (iNOS) from RAW 264.7 stimulated by lipopolysaccharides (LPS).
