Background Older adults are more likely to experience the disorder of skeletal muscles. Objective This study aimed to examine the prevalence of sarcopenia using the diagnostic procedures of sarcopenia recommendedby the Asian Working Group for Sarcopenia in 2019. The association of sarcopenia with physical activity and other factors was also explored. Methods A cross-sectional study was designed. The sample came from a veterans’ home in southern Taiwan during the months of July–September 2018. Sarcopenia was diagnosed according to the Asian Working Group for Sarcopenia (AWGS) criteria in 2019. Skeletal muscle mass and grip strength were determined using bioelectrical impedance analysis and a digital dynamometer, respectively. The walking speed for a 6-m distance was also measured. Furthermore, the Barthel Index (BI), Lawton and Brody Instrumental Activities of Daily Living scales (IADL), mini-mental state examination (MMSE), and body mass index (BMI) were also collected.