8-Hydroxybriaranes from Octocoral Briareum stechei(Briareidae) (Kükenthal, 1908)

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题名:	8-Hydroxybriaranes from Octocoral Briareum stechei(Briareidae) (Kükenthal, 1908)
作者:	Thanh-Hao Huynh;Su-Ying Chien;Junichi Tanaka;Zhi-Hong Wen;Yang-Chang Wu;Tung-Ying Wu;Ping-Jyun Sung
贡献者:	健康暨護理學院
日期:	2021-02
上传时间:	2023-02-24T05:58:34Z (UTC)
摘要:	Chemical investigation of the octocoral Briareum stechei, collected in the Ie Island, Okinawa,Japan, resulted in the isolation of a new briarane-type diterpenoid, briastecholide A (1), as wellas the previously reported metabolites, solenolide C (2) and briarenolide S (3). The structures ofbriaranes 1–3 were characterized through spectroscopic analysis, and the absolute configuration of2 was corroborated by a single-crystal X-ray diffraction analysis. Briarane 3 exhibited bioactivityagainst the protein expression of inducible nitric oxide synthase (iNOS).
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