In fermentation technology courses, a majority of students with non-engineering backgrounds found the fermentation theory content challenging and uninteresting. The primary practical focus of the project involves beer brewing, coupled with collaboration with industry partners such as Winners and breweries in an industry-university cooperation model. This collaboration includes providing access to industry production equipment and addressing industry-oriented problems. Through industry or industry-academia cooperation, students in the classroom are organized into sub-groups, supplemented by a Problem-Based Learning (PBL) approach and a learning-by-doingexperimental course. A 9-item questionnaire was administered using a 5-point scale, with a total of 32 students participating. The results showed that students affirmed that the course enhances their proficiency in biotechnology, the inclusion of guest lectures boosts their enthusiasm for learning, and they perceive theoretical knowledge as crucial for their future careers. Moreover, inviting industry experts to share experiences and providing hands-on experience with related products are beneficial for promoting students’ desire to learn. Additionally, the students' perception after taking the practical course was significantly higher than before they took the practical course regarding enhancing professional competence and learning motivation. Furthermore, female students demonstrated significantly higher performance compared to males. Finally, the researchers provide some implications for future teaching and studies based on the results.
