Briarenols Q–T: Briaranes from A Cultured Octocoral Briareum stechei (Kükenthal, 1908)

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题名:	Briarenols Q–T: Briaranes from A Cultured Octocoral Briareum stechei (Kükenthal, 1908)
作者:	Zhang, Yi-Lin Chiang, Chih-Chao Lee, Yi-Ting Wen, Zhi-Hong Wu, Yang-Chang Yu-JenWu Hwang, Tsong-Long Wu, Tung-Ying Chang, Chia-Yuan Sung, Ping-Jyun
贡献者:	健康暨護理學院
关键词:	Briareum stechei briarane briarenol iNOS COX-2
日期:	2020-07
上传时间:	2020-10-21T07:46:57Z (UTC)
摘要:	Our continuous chemical study of a cultured octocoral Briareum stechei led to the isolation of four new briarane diterpenoids, briarenols Q–T (1–4). The structures of new metabolites 1–4 were established by spectroscopic methods, and compounds 3 and 4 were found to inhibit the generation of inducible nitric oxide synthase (iNOS) from RAW 264.7 stimulated by lipopolysaccharides (LPS).
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